Affecting Factors on Erectile Dysfunction after Radical Prostatectomy and Treatment.
- Author:
In Rae CHO
1
;
Yon Hwan JUNG
;
Keon Cheol LEE
;
Jun Sung JEON
;
Jong Gu KIM
;
Seok San PARK
Author Information
1. Department of Urology, College of Medicine, Inje University, Gimhae, Korea. ircho@ilsanpaik.ac.kr
- Publication Type:Original Article
- Keywords:
Prostate neoplasms;
Prostatectomy;
Erectile dysfunction;
Urinary incontinence
- MeSH:
Cardiovascular Diseases;
Comorbidity;
Diabetes Mellitus;
Erectile Dysfunction*;
Hospital Records;
Humans;
Hypertension;
Incidence;
Male;
Prostatectomy*;
Prostatic Neoplasms;
Quality of Life;
Retrospective Studies;
Risk Factors;
Urinary Incontinence
- From:Korean Journal of Andrology
2005;23(3):122-126
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Radical prostatectomy is the gold standard treatment for clinically localized prostate cancer, a disease whose incidence is increasing. Erectile dysfunction(ED) after radical prostatectomy influences a patient's quality of life significantly. So we evaluated the correlation of preoperative and postoperative factors with postoperative ED and its treatment. MATERIALS AND METHODS: Hospital records of 27 patients who underwent radical prostatectomy by one surgeon at our department were retrospectively reviewed. We performed univariate analyses to correlate preoperative prognostic factors with intaoperative factors and postoperative variables. RESULTS: Excluding 10 patients who had preoperative ED, erectile dysfunction developed in 10 of 17 patients, and the rate was higher in the older age group(p=0.02). Patients underwent non-nerve sparing radical prostatectomy maintained their potency in 0.0% (0/1) comparative with 44.4% (4/9) in unilateral nerve sparing and 42.9% (3/7) in bilateral nerve sparing surgery. Patients with preexisting comorbidity, such as cardiovascular disease(OR=2.38) and margin positivity(OR=4.67) had greater risk of postoperative ED. In 8 erectile dysfunction patients, 3 sildenafil-treated and 2 alprostadil-treated patients showed improvement one year after the operation. CONCLUSIONS: Older patients have greater risk of postoperative ED, and they have more preexisting risk factors including hypertension, cardiovascular disease, diabetes mellitus, and margin positivity.
