Epidemiology of astrovirus infection in children.
- Author:
Hye Sook JEONG
1
;
Ahyong JEONG
;
Doo Sung CHEON
Author Information
- Publication Type:Review
- Keywords: Epidemiology; Acute gastroenteritis; Diarrhea; Human astrovirus; Serotype
- MeSH: Child; Diarrhea; Disease Outbreaks; Gastroenteritis; Hospitalization; Humans; Mamastrovirus; Molecular Epidemiology; Norovirus; Pathology, Molecular; Sprains and Strains; Vomiting
- From:Korean Journal of Pediatrics 2012;55(3):77-82
- CountryRepublic of Korea
- Language:English
- Abstract: Human astrovirus (HAstV) is a major cause of acute diarrhea among children, resulting in outbreaks of diarrhea and occasionally hospitalization. Improved surveillance and application of sensitive molecular diagnostics have further defined the impact of HAstV infections in children. These studies have shown that HAstV infections are clinically milder (diarrhea, vomiting, fever) than infections with other enteric agents. Among the 8 serotypes of HAstV identified, serotype 1 is the predominant strain worldwide. In addition to serotype 1, the detection rate of HAstV types 2 to 8 has increased by using newly developed assays. HAstV is less common compared with other major gastroenteritis viruses, including norovirus and rotavirus; however, it is a potentially important viral etiological agent with a significant role in acute gastroenteritis. A better understanding of the molecular epidemiology and characteristics of HAstV strains may be valuable to develop specific prevention strategies.
