Null and Duplicated Alleles of 17 Y-STR Haplotypes in Koreans and Considerations for Forensic Application.
- Author:
Nam Soo CHO
1
;
Seong Yeon YOO
;
Jung Ho HWANG
;
Ki Min SEONG
;
Nak Eun CHUNG
;
Won Tae LEE
Author Information
1. Department of Forensic Medicine, Central District Office, National Institute of Scientific Investigation, Daejeon, Korea.
- Publication Type:Original Article
- Keywords:
Y chromosome STR;
AmpFlSTR(R) Yfiler(TM) system;
null allele;
duplicated allele;
database
- MeSH:
Alleles;
Haplotypes;
Humans;
Hypogonadism;
Male;
Mitochondrial Diseases;
Ophthalmoplegia;
Rape;
Y Chromosome
- From:Korean Journal of Legal Medicine
2010;34(2):147-151
- CountryRepublic of Korea
- Language:English
-
Abstract:
The analysis of Y chromosome polymorphisms has become common place for the identification of male component in forensic cases. In male/female mixtures of many rape cases, Y-STRs are also very useful for the determination of contributors' number. During the analyses of 17 Y-STR haplotypes for forensic applications using the AmpFlSTR(R) Yfiler(TM) system, a number of null and duplicated alleles (40 out of 2144 subjects) were discovered. Interestingly, two haplotypes should focus the attention on forensic interpretation of Y-STR haplotype profiles, because multiple mutational events at various loci can be interpreted as a wrong mixed or allele drop-out profile.
