A Case of Linear IgA Bullous Dermatosis.
10.5021/ad.1993.5.1.51
- Author:
Yoo Jung HWANG
;
Hong Yoon YANG
;
Chang Woo LEE
;
Joong Hwan KIM
- Publication Type:Case Report
- Keywords:
Linear IgA bullous dermatosis
- MeSH:
Antibodies;
Basement Membrane;
Biopsy;
Buttocks;
Dapsone;
Female;
Fluorescent Antibody Technique, Direct;
Fluorescent Antibody Technique, Indirect;
Humans;
Immunoglobulin A;
Linear IgA Bullous Dermatosis*;
Middle Aged;
Mouth Mucosa;
Skin;
Thigh;
Tongue
- From:Annals of Dermatology
1993;5(1):51-55
- CountryRepublic of Korea
- Language:English
-
Abstract:
This paper deals with a case of linear IgA bullous dermatosis (LABD). The patient was a 58-year-old woman who had multiple pruritic vesicles on the trunk, buttocks, thighs, tongue and buccal mucosa. A biopsy of a lesion revealed subepidermal vesicles. Direct immunofluorescence examination of the perilesional skin showed a linear deposition of IgA along the basement membrane zone (BMZ). Indirect immunofluorescence examination, using NaCl split skin as substrate, showed antiBMZ IgA antibodies bound only to the epidermal side. The skin lesions responded well to oral dapsone therapy.
