Role of Endoscopic Ultrasonography in the Diagnosis of Gastrointestinal Stromal Tumors in the Stomach.
10.5230/jkgca.2005.5.2.120
- Author:
Ji Hoon YOON
1
;
Hyun Chul KIM
;
Chang Soo CHOI
;
Sang Hoon OH
;
Young Kil CHOI
Author Information
1. Department of Surgery, Inje University College of Medicine, Pusan Paik Hospital, Busan, Korea. gsosh@inje.ac.kr
- Publication Type:Original Article
- Keywords:
Gastrointestinal stromal tumor;
Endoscopic ultrasonography (EUS)
- MeSH:
Diagnosis*;
Endosonography*;
Gastrointestinal Stromal Tumors*;
Humans;
Stomach*;
Ulcer
- From:Journal of the Korean Gastric Cancer Association
2005;5(2):120-126
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: Endoscopic ultrasonography (EUS) is a useful imaging procedure for the diagnosis of submucosal tumors in the stomach. The present study investigated the EUS features of benign and malignant gastrointestinal stromal tumors (GISTs) and assessed differences between the two groups. MATERIALS AND METHODS: Thirty patients with a GIST in the stomach were included in the study (23 benign and 7 malignant GISTs). We compared characteristic EUS findings (tumor size, location of tumor, regularity of the outer margin, echo-heterogeneity, presence of cystic spaces, echogenic foci and mucosal ulceration) between benign and malignant GISTs. RESULTS: Tumor sizes over 40 mm were observed in 85.7% of the malignant and 8.7% of the benign tumors (P=0.000). Intralesional cystic spaces were noted in 71.4% of the malignant and 8.7% of the benign tumors (P=0.003). The outer margin was irregular in 71.4% of the malignant and 8.7% of the benign tumors (P=0.014). 85.7% of the malignant and 13.0% of the benign tumors had an echo-heterogeneity in the tumor (P=0.001). The locations of tumor and the presence of echogenic foci or mucosal ulcerations were not different between the two groups. CONCLUSION: Tumor sizes over 40 mm, intralesional cystic spaces, irregular outer margins, and echo-heterogeneity in the tumor were significantly more frequent in malignant GISTs. EUS can provide informations in differentiating benign from malignant GISTs.
