Hepatoid Adenocarcinoma of the Stomach with Liver Metastasis.
10.5230/jkgca.2005.5.2.127
- Author:
Wooil KWON
1
;
Do Joong PARK
;
Hyuk Joon LEE
;
Woo Ho KIM
;
Han Kwang YANG
;
Kuk Jin CHOE
;
Kuhn Uk LEE
Author Information
1. Department of Surgery, Seoul National University College of Medicine, Seoul, Korea. kulee@plaza.snu.ac.kr
- Publication Type:Case Report
- Keywords:
Gastric cancer;
Hepatoid adenocarcinoma;
Liver metastasis
- MeSH:
Adenocarcinoma*;
Carcinoma, Hepatocellular;
Dyspepsia;
Gastrectomy;
Humans;
Liver*;
Lymph Nodes;
Male;
Middle Aged;
Neoplasm Metastasis*;
Prognosis;
Stomach Neoplasms;
Stomach*;
Tomography, X-Ray Computed
- From:Journal of the Korean Gastric Cancer Association
2005;5(2):127-132
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A hepatoid adenocarcinoma of stomach, a subtype of gastric cancr, is characterized by a histologic resemblance to a hepatocellular carcinoma and alpha-feto protein production. Another feature is early metastasis to the liver and lymph nodes, thus revealing a poor prognosis. We report a case of a hepatoid adenocarcinoma of the stomach with liver metastasis. A 52-year-old male visited our hospital with a chief complaint of indigestion. Gastroscopic examination showed a Borrmann type-II lesion on the lesser curvature of the antrum. The CT scan showed a suspected advanced gastric cancer with liver metastasis. The serum AFP level was 123 ng/ml. A radical subtotal gastrectomy and a right hemihepatectomy were performed simultaneously. Pathologic examination confirmed the lesion to be confined to the submucosa. The gastric lesion was a hepatoid adenocarcinoma, and the hepatic lesion was a metastatic adenocarcinoma from the stomach. Therefore, he was classified as having stage IV (T1N1M1) gastric cancer. In cases of a hepatoid adenocarcinoma of the stomach, even patients with early gastric cancer can be staged into the poor prognostic group.
