Effect of Amniotic Membrane Transplantation and Heparin on Tissue Adhesion in Flexor Tenorrhaphy of Chicken.
- Author:
Sung Soo KIM
1
;
Myung Jin LEE
;
IL Kwon CHUNG
;
Man Seok KO
Author Information
1. Department of Orthopedic Surgery, Medical School, Dong-A University, Busan, Korea. tynitus@dau.ac.kr
- Publication Type:Original Article
- Keywords:
Amniotic membrane;
Heparin;
Tenorrhaphy
- MeSH:
Amnion*;
Chickens*;
Fibroblasts;
Heparin*;
Inflammation;
Tendons;
Tissue Adhesions*
- From:Journal of Korean Orthopaedic Research Society
2006;9(1):65-75
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The role of the amniotic membrane with or without heparin was investigated with regard to the prevention of adhesion formation following flexor tenorrhaphy of chicken. MATERIALS AND METHODS: We classified twelve chickens into four groups of three chickens. In group A, the flexor tendon was partially cut and the tendon was repaired. In group B, The repaired tendon was covered with heparin. In group C, the repaired tendon was covered with amniotic membrane. In group D, the repaired tendon was covered with amniotic membrane and heparin. Histologic and gross findings of the repaired tendon were evaluated at postoperative 3, 6 and 9 weeks. RESULTS: In group D, there were less inflammatory cell infiltration and fibroblasts proliferation in all stages. At postoperative 9 weeks of all groups, there were less inflammation and fibroblasts proliferation than those in postoperative 3 and 6 weeks. CONCLUSION: The use of amniotic membrane transplantation and heparin is effective in the prevention of inflammation and adhesion formation following flexor tenorrhaphy of chicken.
