Risk Factors for Subsequent Fracture after Osteoporotic Vertebral Compression Fracture.
10.13004/kjnt.2013.9.2.120
- Author:
Sung Gon KIM
1
;
Joo Chul YANG
;
Tae Wan KIM
;
Kwan Ho PARK
Author Information
1. Department of Neurosurgery, VHS Medical Center, Seoul, Korea. euro3399@naver.com
- Publication Type:Original Article
- Keywords:
Osteoporotic compression fracture;
Bone mineral density;
Cement volume
- MeSH:
Bone Density;
Follow-Up Studies;
Fractures, Compression*;
Humans;
Incidence;
Retrospective Studies;
Risk Factors*;
Spine;
Vertebroplasty
- From:Korean Journal of Neurotrauma
2013;9(2):120-124
- CountryRepublic of Korea
- Language:English
-
Abstract:
OBJECTIVE: Percutaneous vertebroplasty is an effective treatment that relieves pain caused by vertebral compression fracture. However, vertebroplasty may increase the risk for subsequent vertebral compression fracture. The purpose of this study is to evaluate the incidence of and risk factors for subsequent fracture after vertebroplasty. METHODS: A retrospective analysis was performed for 112 patients who were diagnosed with a first osteoporotic compression fracture at a single level and underwent vertebroplasty at that level. Possible risk factors for subsequent fracture, such as age, sex, bone mineral density (BMD), location of treated vertebrae, pattern of cement distribution, cement volume, presence of intradiscal cement leakage, and direction of cement leakage, were analyzed. RESULTS: During the follow-up period, 18 new subsequent vertebral fractures developed (16.1%). Subsequent fractures were more common in osteoporotic patients (T-score < or =-2.5)(p=0.034, r=0.208). Intravertebral cement volume > or =3.5 cc were also associated with a significantly higher risk of fracture (p=0.012, r=0.238). CONCLUSION: Low BMD and volume of intravertebral cement were the factors most strongly associated with subsequent fracture after percutaneous vertebroplasty.
