Evaluation of SD Bioline Strep A for Rapid Antigen Testing in Elementary Schoolchildren.
- Author:
Eun Ha KOH
1
;
Sunjoo KIM
Author Information
1. Department of Laboratory Medicine, Institute of Health Sciences, Gyeongsang National University School of Medicine, Jinju, Korea. sjkim8239@hanmail.net
- Publication Type:Original Article
- Keywords:
Streptococcus pyogenes;
Group A streptococcus;
Rapid antigen test;
Throat culture;
Pharyngitis
- MeSH:
Agar;
Animals;
Anti-Bacterial Agents;
Diagnosis;
Pharyngitis;
Pharynx;
Rats;
Sensitivity and Specificity;
Streptococcus pyogenes
- From:Korean Journal of Clinical Microbiology
2007;10(1):54-58
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Rapid antigen tests (RAT) of group A streptococci (GAS) are easy to perform and can save two days of bacterial culture time. Performance of SD Bioline Strep A was analyzed in comparison with throat culture. METHODS: Three consecutive throat swabs were taken from 308 healthy elementary schoolchildren. The first two swabs were tested for SD Bioline Strep A and Quidel Quick Vue Dipstick Strep A rapid antigen tests, and the third one was inoculated onto blood agar plate to grow GAS. RESULTS: Sensitivity, specificity, positive predictive value and negative predictive value of SD Bioline Strep A were 79.3%, 88.9%, 72.2%, and 92.2% respectively. Those of Quidel Quick Vue Strep A were 58.5%, 93.8%, 77.4%, and 86.2% respectively. CONCLUSION: SD Bioline Strep A showed a significantly higher sensitivity and a slightly lower specificity compared to Quidel Quick Vue Strep A. SD Bioline Strep A RAT should be useful for the rapid diagnosis of bacterial pharyngitis and the optimum use of antibiotics.
