A Case of Epstein-Barr Virus-Associated Hemophagocytic Syndrome Demonstrated by In Situ Hybridization.
- Author:
Dae Kyun KOH
1
;
Soo Joong LEE
Author Information
1. Department of Pediatrics, Catholic University Medical College, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Hemophagocytic syndrome;
Epstein-Barr virus;
In situ hybridization
- MeSH:
Child, Preschool;
Epstein-Barr Virus Infections;
Female;
Fever;
Herpesvirus 4, Human;
Humans;
In Situ Hybridization*;
Lymphohistiocytosis, Hemophagocytic*;
Pediatrics
- From:Journal of the Korean Pediatric Society
1997;40(7):1004-1009
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The virus-associated hemophagocytic syndrome is a disorder characterized by a benign, generalized histiocytic proliferation, with marked hemophagocytosis associated with systemic viral infections. We experienced a case of Epstein-Barr virus (EBV)-associated hemophagocytic syndrome in a 2-year-old female who admitted to our department of pediatrics because of high fever, abdominal distension. Evidence for acute, primary EBV infection was demonstrated with serological and in situ hybridization method. Her presentation, treatment, and clinical course are discussed.
