A Case of Infectious Mononucleosis Associated with Pleural Effusion and Ascites.
- Author:
Seung Kyoo HAN
1
;
Yun Jeong YANG
;
Yon Ho CHOE
;
Yong Hoon JUN
;
Soon Ki KIM
;
Byong Kwan SON
Author Information
1. Department of Pediatrics, College of Medicine, Inha University, Inchon, Korea.
- Publication Type:Case Report
- Keywords:
Infectious mononucleosis;
Pleural effusion;
Ascites
- MeSH:
Anemia, Aplastic;
Anemia, Hemolytic;
Ascites*;
Child;
Child, Preschool;
Communicable Diseases;
Cranial Nerve Diseases;
Diagnosis;
Enzyme-Linked Immunosorbent Assay;
Fever;
Herpesvirus 4, Human;
Humans;
Immunoglobulin G;
Immunoglobulin M;
Infectious Mononucleosis*;
Leukocytosis;
Lung Diseases, Interstitial;
Lymphatic Diseases;
Lymphocytosis;
Male;
Meningoencephalitis;
Myelitis, Transverse;
Myocarditis;
Orchitis;
Pharyngitis;
Pleural Effusion*;
Purpura, Thrombocytopenic, Idiopathic;
Rupture;
Spleen;
Splenomegaly;
Vomiting;
Young Adult
- From:Journal of the Korean Pediatric Society
1997;40(7):1026-1030
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Infectious mononucleosis is an acute infectious disease occurring predominantly in older children and young adults due to primary Epstein-Barr virus infection. The clinical picture is extremely variable in both severity and duration. The disease in children is generally mild. It is characterized clinically by fever, exudative or membranous pharyngitis, generalized lymphadenopathy, and splenomegaly. Rarely, it complicates neurologic involvement such as cranial nerve palsy, meningoencephalitis, and transverse myelitis, hematologic involvement such as hemolytic anemia, immune thrombocytopenic purpura, and aplastic anemia, rupture of spleen, myocarditis, interstitial pneumonia, and orchitis, etc. We experienced a case of infectious mononucleosis with pleural effusion and ascites in a 5-year-old male with the chief complaint of fever, sore throat and vomiting 3 days prior to admission. The diagnosis was made on the clinical findings, immunologic findings and the typical findings of peripheral blood smear. On peripheral blood smear, leukocytosis with atypical lymphocytosis were seen. On immunologic study, anti-VCA IgM and IgG were positive by ELISA method. We reported this case and reviewed related literatures briefly.
