Usefulness of the Controlled Attenuation Parameter for Detecting Liver Steatosis in Health Checkup Examinees.
- Author:
Ja Kyung KIM
1
;
Kwan Sik LEE
;
Jung Ran CHOI
;
Hyun Jung CHUNG
;
Da Hyun JUNG
;
Kyung Ah LEE
;
Jung Il LEE
Author Information
- Publication Type:Original Article ; Evaluation Studies ; Research Support, Non-U.S. Gov't
- Keywords: Fatty liver; Controlled attenuation parameter; Ultrasonography; Early diagnosis; Metabolic syndrome
- MeSH: Adult; Body Mass Index; Body Weight; Elasticity Imaging Techniques/*methods; Fatty Liver/*ultrasonography; Female; Humans; Liver/*ultrasonography; Male; Middle Aged; Physical Examination/*methods; Predictive Value of Tests; ROC Curve; Retrospective Studies; Severity of Illness Index
- From:Gut and Liver 2015;9(3):405-410
- CountryRepublic of Korea
- Language:English
- Abstract: BACKGROUND/AIMS: The controlled attenuation parameter (CAP) implemented in FibroScan(R) is reported to be a non-invasive means of detecting steatosis (>10% steatosis). We aimed to evaluate the usefulness of CAP in detecting steatosis among health checkup examinees and to assess its correlation with ultrasonography (US). METHODS: Consecutive CAP results were retrospectively collected. A total of 280 subjects were included. RESULTS: Fatty liver was detected in 119 subjects (42.5%) by US, whereas it was detected in 160 subjects (57.1%) by the CAP. The numbers of subjects with S0:S1:S2:S3 steatosis according to the CAP value were 120:59:58:43, respectively. The mean CAP values were 203.34+/-28.39 dB/m for S0, 248.83+/-6.14 dB/m for S1, 274.33+/-8.53 dB/m for S2, and 322.35+/-22.20 dB/m for S3. CAP values were correlated with body weight (r=0.404, p<0.001), body mass index (r=0.445, p<0.001), and the fatty liver grade by US (r=0.472, p<0.001). Among the 161 subjects with normal US findings, steatosis was detected in 65 subjects (40.4%) using the CAP. CONCLUSIONS: The CAP seems to be useful for detecting very low-grade hepatic steatosis in health checkup examinees. Its role in predicting subjects with a risk of metabolic derangement needs to be evaluated.
