Evaluation of the Automatic Blood Bank Instrument AutoVue Innova for Antibody Screening.
- Author:
Sun Hyung KIM
1
;
Deok Hwa NAM
;
Jin Hyuk YANG
;
Soo Young YOON
;
Young Kee KIM
;
Kap No LEE
;
Chae Seung LIM
Author Information
1. Department of Laboratory Medicine, College of Medicine, Korea University, Seoul, Korea. malarim@korea.ac.kr
- Publication Type:Comparative Study ; Original Article
- Keywords:
Antibody screening;
Automatic blood bank instrument;
AutoVue Innova
- MeSH:
Automation;
Blood Banks;
Mass Screening
- From:Korean Journal of Blood Transfusion
2008;19(2):140-145
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Pre-transfusion tests are important for performing safe transfusion and there is a need to standardize the process of these tests. In blood banks, automation of tests is under developed and there is always a high risk of error. Automatic instruments for blood bank tests are used in blood centers where a great volume of tests are performed. However, other small scale hospitals have little experience with automatic blood bank instruments. Here, we evaluated the newly developed automatic instrument, the AutoVue Innova (Ortho-Clinical Diagnostics, Raritan, NJ, USA), for performing unexpected antibody screening tests and we compared this to other well known systems. METHODS: In a comparative study, a total of 136 samples, including 28 antibody screening positive samples and 108 negative samples, were tested in parallel by the LISS/Coombs card (DiaMed Ag, Cresssier, Morat, Switzerland) and the AutoVue Innova. The positive samples that were proven by the LISS/Coombs card and the AutoVue Innova were identified by the ID-DiaCell panel (DiaMed Ag, Cresssier, Morat, Switzerland) and the 0.8% Resolve Panel A (Ortho, Raritan, NJ, USA), respectively. Discrepant samples were rechecked by the Identisera Diana (Diagnostic Grifols, Barcelona, Spain). RESULTS: Among the 136 samples, 134 results (98.5%) of the AutoVue Innova agreed with those of the LISS/Coombs card and 2 results were discrepant. These two results were antibody screening positive only on the AutoVue and they were identified as being anti-Lewis(a). CONCLUSION: The unexpected antibody screening tests using the AutoVue Innova showed reliable results for general accuracy and they were useful in aspect of a decreased workload and increased safety, and even for less experienced persons.
