Renal Cell Carcinoma Occurred in One Family.
- Author:
Il Soon PARK
1
;
Yeo Deuk YOON
;
Heung Gi KIM
;
Sung Kwang CHUNG
Author Information
1. Department of Urology, College of Medicine, Kyungpook National University, Taegu, Korea.
- Publication Type:Case Report
- Keywords:
familial renal cell carcinoma
- MeSH:
Carcinoma, Renal Cell*;
Chromosome Aberrations;
Humans;
Karyotype;
Leukocytes;
Nephrectomy;
Pedigree;
Siblings
- From:Korean Journal of Urology
1989;30(6):934-938
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The etiology of renal cell carcinoma has not been clarified and the familial renal cell carcinoma accompanied with karyotypic abnormalities is very rarely reported in the world literatures. Recently the approaches to evaluate the etiology of renal cell carcinoma are now being tried but it's relationship with the chromosomal abnormalities has not yet been clearly identified. We report two cases of renal cell carcinoma occurred in sister and brother who were treated with radical nephrectomy. And also we studied the pedigree of the family and the karyotype of peripheral leukocytes from four siblings which shows normal chromosomal patterns
