Functional Magnetic Resonance Imaging with Arterial Spin Labeling: Techniques and Potential Clinical and Research Applications.
10.13104/imri.2017.21.2.91
- Author:
Ju Ho KIM
1
;
Dae Seob CHOI
;
Sung Eun PARK
;
Ho Cheol CHOI
;
Seong Hu KIM
Author Information
1. Department of Radiology, Gyeongsang National University Hospital, Jinju, Korea. choids@gnu.ac.kr
- Publication Type:Original Article
- Keywords:
Cerebral blood flow (CBF);
Arterial spin labeling (ASL);
Blood oxygenation level-dependent (BOLD);
Functional MRI (fMRI);
Resting state fMRI
- MeSH:
Brain;
Cerebellum;
Frontal Lobe;
Magnetic Resonance Imaging*;
Motor Cortex;
Oxygen;
Perfusion Imaging
- From:Investigative Magnetic Resonance Imaging
2017;21(2):91-96
- CountryRepublic of Korea
- Language:English
-
Abstract:
PURPOSE: To describe technical methods for functional magnetic resonance imaging (fMRI) study with arterial spin labeling (ASL) compared to blood oxygenation level-dependent (BOLD) technique and discuss the potential of ASL for research and clinical practice. MATERIALS AND METHODS: Task-based (n = 1) and resting-state fMRI (rs-fMRI) (n = 20) were performed using ASL and BOLD techniques. Results of both techniques were compared. RESULTS: For task-based fMRI with finger-tapping, the primary motor cortex of the contralateral frontal lobe and the ipsilateral cerebellum were activated by both BOLD and ASL fMRI. For rs-fMRI of sensorimotor network, functional connectivity showed similar results between BOLD and ASL. CONCLUSION: ASL technique has potential application in clinical and research fields because all brain perfusion imaging, CBF measurement, and rs-fMRI study can be performed in a single acquisition.
