Neurotoxic Syndrome Developed after Taking Sertraline and Risperidone.

Author: Jeong Min KIM ¹ ; Soon Tae LEE ; Eun Cheol SONG ; Keun Hwa JUNG ; Dong In SINN ; Hakjae CHUNG ; Kon CHU ; Manho KIM
Author Information

1. Department of Neurology, Clinical Research Institute, Seoul National University Hospital, Seoul, Korea. kimmanho@snu.ac.kr
Publication Type:Case Report
Keywords: Neuroleptics; Serotonin syndrome; Sertraline; Risperidone
MeSH: Antipsychotic Agents; Humans; Neuroleptic Malignant Syndrome; Risperidone*; Serotonin Syndrome; Sertraline*; Young Adult
From:Journal of Clinical Neurology 2007;3(3):165-167
CountryRepublic of Korea
Language:English
Abstract: Neuroleptic malignant syndrome and serotonin syndrome share many common clinical features, and the term "Neurotoxic syndrome" can be used when a clear distinction cannot be made between the two. Here we present a case of 19-year-old man who experienced serotonin syndrome caused by sertraline intake, and consecutive neuroleptic malignant syndrome by risperidone. This case suggests that these two syndromes can be concomitantly induced in some patients who are susceptible to these drugs. Clinicians may have to pay close attention to this problem when prescribing drugs to patients who previously showed sensitivity to CNS-acting drugs.