Clinical analysis of decompressive craniectomy and lobectomy in patients with malignant cerebral infarction.
- Author:
Sang Hyun AHN
1
;
Chan Young CHOI
;
Seong Rok HAN
;
Gi Taek YEE
;
Moon Jun SOHN
;
Chae Hyuck LEE
Author Information
1. Department of Neurosurgery, Ilsan Paik Hospital, College of Medicine, Korea. cychoi@ilsanpaik.ac.kr
- Publication Type:Original Article
- Keywords:
Decompressive craniectomy;
Lobectomy;
Malignant cerebral artery infarction
- MeSH:
Anterior Cerebral Artery;
Cerebral Infarction;
Decompressive Craniectomy;
Female;
Follow-Up Studies;
Glasgow Coma Scale;
Humans;
Male;
Medical Records;
Middle Cerebral Artery;
Posterior Cerebral Artery;
Retrospective Studies;
Stress, Psychological;
Survival Rate
- From:Korean Journal of Cerebrovascular Surgery
2008;10(3):448-453
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: The use of decompressive craniectomy for treating massive cerebral infarction is attracting much attention because conventional medical treatment is associated with high mortality. The aim of this retrospective study was to evaluate the surgical treatment results and prognostic factors for patients suffering with malignant cerebral infarction. METHODS: We analyzed 9 consecutive patients who underwent decompressive craniectomy with or without temporal lobectomy after malignant cerebral infarction from 2000 to 2008. We reviewed the medical records, the radiological finding and the pre-operative clinical assessment using the Glasgow Coma scale (GCS). The postoperative functional outcome was assessed as the Barthel-Index (BI) and the modified Rankin scale (mRS). RESULTS: The male to female ratio was 3.5:1. The mean age was 50 years (range: 36-68). Eight patients (89%) showed involvement of the entire middle cerebral artery (MCA) territory and the concomitant anterior cerebral artery (ACA) or posterior cerebral artery (PCA) territory. The preoperative mean GCS was 8.3 (range: 5-12) and the mean time to surgery after the onset of symptoms was 47.7 hours (range: 4-168 hours). All the patients underwent decompressive craniectomy and duroplasty. Among them, four patients (45%) underwent temporal lobectomy. The mean followup period was 7.3 months (range: 1-26 months) and five patients died within this period. CONCLUSION: Decompressive craniectomy with or without lobectomy for patients with malignant cerebral infarction decreases the mortality rate and it improves the functional outcome. In the survived group, comparison of the two surgical modalities didn't show any statistically significant difference. However, the decompressive craniectomy with lobectomy group demonstrated a high survival rate (75%). Future studies are needed to investigate the proper treatment modalities for malignant cerebral infarction.
