Pathophysiology and Treatment Guidelines of Dysfunctional Uterine Bleeding.
- Author:
Kyu Sup LEE
1
Author Information
1. Department of Obstetrics and Gynecology, College of Medicine, Pusan National University, Busan, Korea. kuslee@pusan.ac.kr
- Publication Type:Review
- Keywords:
Dysfunctional uterine bleeding;
Pathophysiology;
Treatment
- MeSH:
Contraceptives, Oral, Combined;
Danazol;
Endometrial Ablation Techniques;
Female;
Gonadotropin-Releasing Hormone;
Hemorrhage;
Humans;
Hysterectomy;
Levonorgestrel;
Menstrual Cycle;
Metrorrhagia*;
Progesterone;
Tranexamic Acid;
Women's Health
- From:Korean Journal of Obstetrics and Gynecology
2005;48(6):1390-1401
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Dysfunctional uterine bleeding (DUB) is the major cause of heavy menstrual bleeding during reproductive years and impacts on women's health both medically and socially. The pathophysiology of DUB is largely unknown but occurs in both ovulatory and anovulatory menstrual cycles. Medical treatments include tranexamic acid, nonsteroidal antiinflammatory drugs, combined oral contraceptives, progesterone, danazol, and GnRH analogue. Surgical treatments include endometrial ablation and hysterectomy. Since none of the treatments for DUB is superior to one of the others, and since all treatments have their advantages and disadvantages, counselling and management of patients with DUB should incorporate medical approach, levonorgestrel releasing IUD, endometrial ablation and hysterectomy.
