A Successful Surrogate Pregnancy in a Patient with Mayer-Rokitansky-Kuster-Hauser Syndrome.
- Author:
Mi Young HAN
1
;
In Jeong HEO
;
Hyun Ju PARK
;
Hyun Jin LEE
;
Eun Hee LEE
Author Information
1. Department of Obstetrics and Gynecology, Ilsin Christian Hospital, Pusan, Korea. gigibe430@hanmail.net
- Publication Type:Case Report
- Keywords:
Mayer-Rokitansky-Kuster-Hauser Syndrome;
Surrogate pregnancy
- MeSH:
Amenorrhea;
Down-Regulation;
Fathers;
Female;
Gonadotropin-Releasing Hormone;
Gonadotropins;
Humans;
Infertility;
Oocytes;
Parturition;
Pregnancy*;
Uterus;
Vagina
- From:Korean Journal of Obstetrics and Gynecology
2005;48(6):1533-1539
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Lack of mullerian development (Mayer-Rokitansky-Kuster-Hauser Syndrome) is characterized by absence of apparent vagina and/or uterus, normal secondary sexual characteristics, normal reproductive hormonal profile, and a relatively common cause of primary amenorrhea about 1 in 4,000 female births and also cause of primary infertility. Management for these women comprise of construction of neovagina for sexual life. In 1985, the first report of a successful pregnancy through the uterine surrogacy was made. It is being possible for these women to have new opportunity of getting her own genetic offspring. Since ovarian activity is completely preserved in patients, controlled ovarian hyperstimulation is similar to any other IVF case that is with urinary or recombinant gonadotropins following GnRH agonist down regulation. Genetic offspring can be achieved by cellection of oocytes from the genetic mather, in-vitro-fertilization by the genetic father, and placement into a surrogate carrier. We have experienced a case of successful surrogate pregnancy in a patient with congenital absence of vagina and uterus.
