A Case Of Periventricular Leukomalacia Related To Chorioamnionitis.
- Author:
Young Sun AHN
1
;
Kyung SEO
;
Jong Hwa KIM
;
Sung Rok PARK
;
Jong Seung SHIN
Author Information
1. Department of Obstetrics & Gynecology, Yonsei University, College of Medicine, Seoul, Korea.
- Publication Type:Case Report
- Keywords:
Periventricular leukomalacia;
Chorioamnionitis;
Perinatal asphyxia
- MeSH:
Asphyxia;
Chorioamnionitis*;
Female;
Humans;
Hypoxia, Brain;
Incidence;
Infant, Newborn;
Infant, Premature;
Leukomalacia, Periventricular*;
Pathology;
Perfusion;
Placenta;
Pregnancy
- From:Korean Journal of Obstetrics and Gynecology
2002;45(8):1411-1415
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Periventricular leukomalacia is a major cause of neuro-developmental delay in premature infant. Although it develops in only a small percentage of preterm infants, the condition poses a major problem. The pathogenesis of periventricular leukomalacia is not well established. Because of the topography of the lesion, a decreased cerebral perfusion occurred before delivery is thought to be a critical pathogenetic factor. Therefore, hypoxic brain damage is thought to be a major cause of periventricular leukomalacia. The importance of neurochemically mediated injury to the white matter has been stressed. Recently, high incidence of placental chorioamnionitis with periventricular leukomalacia. We experienced a case of periventricular leukomalacia related to chorioamnionitis. The pathology of placenta was chorioamniontis, and it was thought to be a cause of periventricular leukomalacia. So, we report our case with a short literature review to ensuring that chorioamionitis without perinatal asphyxia cause a periventricular leukomalacia.
