Short- & Long-term Effectiveness of Intracavitary Urokinase in Loculated Thoracic Empyema.
10.3348/jkrs.1995.32.1.115
- Author:
Young Min HAN
;
Ki Chul CHOI
;
Chong Soo KIM
;
Gyung Ho CHUNG
;
Myung Hee SOHN
;
Tae Gon JEONG
- Publication Type:Original Article
- MeSH:
Catheters;
Drainage;
Empyema;
Empyema, Pleural*;
Fluoroscopy;
Humans;
Recurrence;
Thorax;
Tomography, X-Ray Computed;
Ultrasonography;
Urokinase-Type Plasminogen Activator*
- From:Journal of the Korean Radiological Society
1995;32(1):115-119
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: The purpose of this study was to evaluate the short- and long-term effectivensess of intracavitary urokinase with percutaneous catheter drainage in Ioculated thoracic empyemas. MATERIALS AND METHODS: 15 patients were identified as second stage of Ioculated thoracic empyema by estimating nature of pleural fluid, chest PA, lateral decubitus view and CT scan. Under the guidance of fluoroscopy or ultrasound, catheter was inserted percutaneously. Instillation of urokinase was started when amount of drained fluid became less than 30ml per day with 100,000U of urokinase mixed with 100ml of normal saline. Trial of urokinase was repeated until complete drainage of empyema was demonstrated on plain chest film obtained after 48 hours. RESULTS: Successful complete drainage was achieved in 14 of 15 patients. In long-term study, complete resorption was demonstrated in 11 of 12 patients. Average dosage of used urokinase was 330,000U and mean duration of catherter insertion was 35 days. CONCLUSION: lntracavitary urokinase with percutaneous catheter drainage is a safe and effective method to facilitate drainage of Ioculated empyema and to prevent recurrence.
