Treatment of Recalcitrant Rosacea with 13 - Cis - Retinoic Acid.
- Author:
Hoon HUR
;
Kyu Uang WHANG
;
Chang Woo LEE
;
Jae Hong KIM
;
Joong Hwan KIM
- Publication Type:Original Article
- Keywords:
Recalcitrant rosacea;
13 - Cis - retinoic acid
- MeSH:
Cheilitis;
Humans;
Isotretinoin;
Male;
Metronidazole;
Nose;
Rosacea*;
Telangiectasis;
Tetracycline;
Tretinoin*
- From:Korean Journal of Dermatology
1986;24(2):238-241
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Eight men with a one-ta-seven-year history of rosacea which poorly controlled by oral tetracycline or metronidazole, with or without topical medications, were given 13-cis-retinoic acid in dosages of p.5 to 0. 7 mg/kg/day for eight weeks. The size of erytherna and the number of papules had been gradually decreased since the second week of treatment. Eight weeks later more than 75p, regression was recognized in six patients, however telangiectasia remained unchanged. All eight patients complained of only mild degrees of cheilitis and dryness of the nose, and had no evidence of the serologic abnormalities on the tests examined during the period of therapy.
