A Case of Candida glabrata Esophagitis.
- Author:
Jung Hoon LEE
1
;
Ok Jae LEE
;
Hyun Joo MIN
;
Do Yeon KANG
;
In Gyu MOON
;
Kee Dong LEE
;
Hyun Jeen KIM
;
Tae Hyo KIM
;
Woon Tae JUNG
Author Information
1. Department of Internal Medicine, Gyeongsang National University College of Medicine, Jinju, Korea. ojlee@nongae.gsnu.ac.kr
- Publication Type:Case Report
- Keywords:
Candidial esophagitis;
Candida glabrata
- MeSH:
Amphotericin B;
Anti-Bacterial Agents;
Antifungal Agents;
Candida albicans;
Candida glabrata*;
Candida*;
Danazol;
Esophagitis*;
Fluconazole;
Humans;
Mortality
- From:Korean Journal of Gastrointestinal Endoscopy
2003;27(4):211-215
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Candida species are the most common cause of all cases of infectious esophagitis, and Candida albicans is the main causative organism of these infections. Candida glabrata has been considered a relatively nonpathogenic saprophyte of the normal flora of healthy individuals, rarely causing serious infection in human. However, following the widespread and increased use of broad-spectrum antibiotics and immunosuppressive therapy, the frequency of infections caused by C. glabrata has increased significantly. C. glabrata is of special importance because C. glabrata infections are associated with a highest mortality rate and resistant to azole antifungal agents, especially fluconazole. We report a case of C. glabrata esophagitis resistant to fluconazole but treated effectively with amphotericin B.
