A Case of Secondary Amyloidosis Associated with Intestinal Tuberculosis.
- Author:
Jungkwon KIM
1
;
Seung Jae MYUNG
;
Jungjoon CHOI
;
Gideog KIM
;
Dongryoul OH
;
Sujin KOH
;
Won Jang KIM
;
Jintae PARK
;
Ginhyuk LEE
;
Suk Kyun YANG
;
Weon Seon HONG
;
Jin Ho KIM
;
Young Il MIN
;
Jooryung HUH
Author Information
1. Department of Internal Medicine, University of Ulsan College of Medicine, Asan Medical Center, Seoul, Korea. sjm5675@amc.seoul.kr
- Publication Type:Case Report
- Keywords:
Amyloidosis;
Intestinal tuberculosis
- MeSH:
Amyloidosis*;
Colonoscopy;
Diarrhea;
Female;
Gastrointestinal Tract;
Humans;
Inflammation;
Middle Aged;
Mucous Membrane;
Plaque, Amyloid;
Rectum;
Serum Amyloid A Protein;
Tomography, X-Ray Computed;
Tuberculosis*
- From:Korean Journal of Gastrointestinal Endoscopy
2003;27(4):244-248
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
The secondary amyloidosis (AA type), a complication of inflammation or infection, is caused by the deposition of serum amyloid protein A in various organs. The clinical manifestations of amyloidosis are various according to involved organs. The gastrointestinal tract is one of the commonly affected organs. However, the endoscopic findings of gastrointestinal amyloidosis are nonspecific, and symptoms are diverse. Hepatic involvement of amyloidosis rarely leads to hepatic dysfunction, threfore is not a clinical concern. We report a 54-year-old women with intestinal tuberculosis whose major symptom was watery diarrhea lasting several months. The amyloid deposits were histologically proven in the rectum of which mucosa showed redness and swelling endoscopically and hepatic involvement of amyloidosis was suspected on abdominopelvic CT scan. After anti-tuberculosis medication for 6 months, abdominopelvic CT scan showed resolution of hepatic involvement and colonoscopy revealed improvement of redness and loss of vascularity of the rectum.
