Homograft or Autograft Valve Replacement.
- Author:
Byung Chul CHANG
1
;
Sak LEE
Author Information
1. Department of Thoracic and Cardiovascular Surgery, Yonsei University College of Medicine, Korea. bcchang@yumc.yonsei.ac.kr
- Publication Type:Review
- Keywords:
Autograft;
Homograft;
Valve replacement
- MeSH:
Adult;
Allografts*;
Aortic Valve;
Autografts*;
Child;
Endocarditis;
Hemodynamics;
Humans;
Incidence;
Infant;
Pulmonary Valve
- From:Hanyang Medical Reviews
2007;27(2):44-48
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Since 1960s, when Ross and Barratt-Boyes introduced homograft replacement of the aortic valve, the valvular replacement using homografts or autografts has been gained increasing acceptance. Aortic or pulmonary valves (with or without associated vascular conduits) transplanted from one individual to another have exceptionally good hemodynamic profiles, a low incidence of thromboembolic complications without chronic anticoagulation, and a low re-infection rate following valve replacement for endocarditis. The homografts were primarily used for complex congenital reconstructions in infants, and children. However, more recently they have been increasingly used in adults requiring aortic valve replacement. Even though there are many advantages, the lack of available homografts, as well as concerns of long-term stenotic problems, may limit their use.
