Polycythemia Vera Presenting with Generalized Chorea: A Case Report and Review of the Literature.
10.3904/kjm.2014.87.5.619
- Author:
Sun Woong KIM
1
;
Hyung Min YU
;
Yoon Jeong LEE
;
Hee Jin KIM
;
Mina HUR
;
Hong Ghi LEE
Author Information
1. Department of Internal Medicine, Konkuk University Medical Center, Konkuk University School of Medicine, Seoul, Korea. mlee@kuh.ac.kr
- Publication Type:Case Report
- Keywords:
Polycythemia vera;
Chorea disorders
- MeSH:
Aged;
Aspirin;
Chorea*;
Extremities;
Female;
Head;
Headache;
Humans;
Hydroxyurea;
Neurologic Manifestations;
Phlebotomy;
Polycythemia;
Polycythemia Vera*;
Tinnitus
- From:Korean Journal of Medicine
2014;87(5):619-624
- CountryRepublic of Korea
- Language:English
-
Abstract:
Polycythemia vera (PV) is a myeloproliferative neoplasm characterized by erythrocytosis. Clinical symptoms can range in severity from headache and tinnitus to thrombohemorrhagic complications. Neurologic symptoms are common at the onset of polycythemia; however, chorea due to PV is a rare complication. We present the case of a 77-year-old female who was referred to our hospital because of choreic movement of the limbs, head and face. She was diagnosed with JAK2V617F mutation-positive PV. Her chorea was completely resolved by phlebotomy combined with hydroxyurea and aspirin.
