Glucocorticoid Triggers an Attack of Periodic Hypokalemic Paralysis during Treatment for Diffuse Large B-cell Lymphoma.
10.3904/kjm.2014.87.5.625
- Author:
Kyung Sun HA
1
;
Young Jae PARK
;
Sung Soo PARK
;
Joon Yub LEE
;
Ji Hyun KIM
;
Inae JANG
;
Jae Ho BYUN
Author Information
1. Department of Internal Medicine, College of Medicine, The Catholic University of Korea, Seoul, Korea. jhbyun37@catholic.ac.kr
- Publication Type:Case Report
- Keywords:
Hypokalemic periodic paralysis;
Diffuse large B-cell lymphoma
- MeSH:
Drug Therapy;
Drug Therapy, Combination;
Humans;
Hypokalemic Periodic Paralysis;
Lower Extremity;
Lymphoma, B-Cell*;
Paralysis*;
Potassium;
Prednisolone
- From:Korean Journal of Medicine
2014;87(5):625-629
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Hypokalemic periodic paralysis is a rare disorder characterized by sudden onset of weakness and low serum potassium levels. We report a case provoked by combination chemotherapy including prednisolone. A 23-yr-man, diagnosed with diffuse large B-cell lymphoma, received chemotherapy. He developed significant weakness in upper and lower extremities during chemotherapy, and his serum potassium level was 1.7 mmol/L. Potassium replacement restored the weakness. Further workup revealed that prednisolone had provoked hypokalemic paralysis. As prednisolone triggered an attack of hypokalemic periodic paralysis, it should be administered with caution, particularly in patients with periodic paralysis.
