Effect of Major Depressive Disorder and Insomnia on Somatization.
- Author:
Jin Yong JUN
;
Seog Ju KIM
;
Yu Jin LEE
;
Seong Jin CHO
- Publication Type:Original Article
- Keywords:
Depression;
Insomnia;
Somatization
- MeSH:
Axis, Cervical Vertebra;
Depression;
Depressive Disorder, Major;
Diagnostic and Statistical Manual of Mental Disorders;
Female;
Humans;
Male;
Surveys and Questionnaires;
Republic of Korea;
Sleep Initiation and Maintenance Disorders
- From:Sleep Medicine and Psychophysiology
2012;19(2):84-88
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
INTRODUCTION: The objective of the present study was to investigate the independent effects of major depressive disorder (MDD) and insomnia on somatization, respectively. METHODS: A total of 181 participants (73 males and 108 females ; mean age 41.59+/-8.92) without serious medical problem were recruited from a community and a psychiatric clinic in Republic of Korea. Subjects were divided into 4 groups based on the Structured Clinical Interview for DSM-IV axis I disorder (SCID-IV) and sleep questionnaire : 1) normal controls (n=127), 2) primary insomnia (n=11), 3) MDD without insomnia (n=14), and 4) MDD with insomnia (n=29). All participants were requested to complete the somatization subscores of the Symptom Checklist-90-Revised (SCL-90-R). RESULTS: There were significant between-group differences in somatization score (F=25.30, p<0.001). Subjects with both MDD and insomnia showed higher somatization score compared to normal control (p<0.001), subjects with primary insomnia (p=0.01), or MDD subjects without insomnia (p<0.001). Subjects with primary insomnia had higher somatization score than normal controls (p<0.01), while there was no significant difference between MDD subjects without insomnia and normal controls. In multiple regression, presence of insomnia predicted higher somatization score (beta=0.44, p<0.001), while there was only non-significant association between MDD and somatization (beta=0.14, p=0.08). CONCLUSION: In the current study, insomnia was associated with somatization independently from major depression. Subjects with primary insomnia showed higher somatization. Within MDD patients, presence of insomnia was related to higher somatization. Our finding suggests that insomnia may partly mediate the relationship between depression and somatization.
