Amniotic Membrane Transplantation for Late-Onset Filtering Bleb Leaks.
- Author:
Tae Woo KIM
1
;
Jong Hyun KIM
;
Dong Myung KIM
Author Information
1. Department of Ophthalmology, Seoul National University College of Medicine, Korea.
- Publication Type:Original Article
- Keywords:
Amniotic membrane;
Late-onset filtering bleb leak
- MeSH:
Amnion*;
Blister*;
Humans;
Transplants
- From:Journal of the Korean Ophthalmological Society
2001;42(1):208-211
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Successful treatment of late-onset leakage of filtering bleb often requires conjunctival advancement or conjunctival graft with the risk of bleb failure. The authors performed amniotic membrane transplantation in two patients with Seidel-positive late-onset leakage of filtering bleb. In one patient, amniotic membrane transplantation(AMT)was performed twice. In the patient who underwent AMT twice, the bleb became Seidel-negative within 5 weeks of second AMT. However, it became Seidel-positive again within next 7 weeks. In the other patient, the bleb leak was partially resolved within 4 weeks, but became exuberant again within the next 4 weeks. In our experience, AMT had only a limited benefit in treating Seidel-positive bleb leaks. However, its initial success suggests that further studies are necessary to better understand the role of amniotic membrane in bleb leak and to develop a potential therapeutic modality for treating late-onset filtering bleb leak.
