Surgical Outcome of Intractable Seizure with Space-Occupying Lesion in Temporal Lobe.
- Author:
Jun Bum PARK
1
;
Wan Su LEE
;
Jung Kyo LEE
;
Sang Ryong JEON
;
Jeong Hoon KIM
;
Sung Woo ROH
;
Young Shin RA
;
Chang Jin KIM
;
Byung Duk KWUN
;
Joong Koo KANG
;
Yang KWON
;
Seung Chul RHIM
;
Sang Ahm LEE
;
Tae Sung KO
Author Information
1. Department of Neurosurgery, Asan Medical Center, College of Medicine, Ulsan University, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Temporal lobe epilepsy;
Anterior temporal lobectomy;
Lesionectomy
- MeSH:
Anterior Temporal Lobectomy;
Brain;
Epilepsy;
Epilepsy, Temporal Lobe;
Hippocampus;
Humans;
Magnetic Resonance Imaging;
Neuroimaging;
Seizures*;
Temporal Lobe*
- From:Journal of Korean Neurosurgical Society
2001;30(1):26-32
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: The increasing use of sensitive neuroimaging techniques has demonstrated that significant percentage of patients with intractable complex partial seizures have brain masses, especially in temporal lobe. The optimal surgical solution for these patients is still open to debate. The purpose of our investigation is to evaluate the surgical outcome of patient with lesion-related temporal lobe epilepsy with respect to the types of surgery and the location of lesion. PATIENTS AND METHODS: From DEC. 1993 to Dec. 1997, 35 patients with intractable epilepsy and space occupying temporal lobe lesion identified in preoperative MRI were included in this study. The types of surgery were lesionectomy, anterior temporal lobectomy with or without hippocampectomy. The location of lesion was divided as anteromedial group and lateral cortical group. The postoperative seizure outcomes according to the type of surgery and location of the lesion were compared. RESULTS: Twenty-six of 34 patients(76.5%) were seizure-free after surgery. The Engel's class was favorable after anterior temporal lobectomy with or without hippocampectomy(p=.044). CONCLUSION: It is favorable to perform anterior temporal lobectomy for the treatment of intractable epilepsy with space-occipying lesion in temporal lobe. The resection of the hippocampus can be individualized.
