Antibiotic prophylaxis in the operation of the closed mandibular fractures and the efficacy of postoperative antibiotics.
- Author:
Sang Hoon KANG
1
;
Young Su CHOI
;
In Young BYUN
;
Moon Key KIM
Author Information
1. Department of Oral and Maxillofacial Surgery, National Health Insurance Corporation Ilsan Hospital, Korea. Jewon98@kornet.net
- Publication Type:Original Article
- Keywords:
Mandible fracture;
Open reduction;
Prophylactic antibiotics;
Surgical site infection
- MeSH:
Anti-Bacterial Agents;
Antibiotic Prophylaxis;
Drainage;
Fever;
Humans;
Incidence;
Mandibular Fractures;
Wound Infection
- From:Journal of the Korean Association of Oral and Maxillofacial Surgeons
2009;35(1):31-34
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
PURPOSE: This study compared the frequency of postoperative infections in patients for a closed mandibular fracture with that without the ostoperative antibiotic prophylaxis. Patients and Methods: 48 patients without any specific medical history were divided into two groups depending on whether or not antibiotics had been applied after the surgery. The 24 patients in group 1 received only a second-generation cephalosporin (Cefotetan(R)) ntravenously from admission to immediate after the surgery. Likewise, 24 patients in group 2 received 1.0g of Cefotetan(R) twice daily longer than the third day after surgery. The mean (SD) duration of antibiotics administration after surgery was 6.9 (+/-3.56). The patients were evaluated after surgery for any postoperative infections according to the criteria: purulent drainage from a wound, spontaneous wound dehiscence accompanied by swelling, pain, and fever around the wound. RESULTS: Postoperative infections were encountered in 2 out of 24 patients in group 1, who received antibiotic medication until shortly after surgery, and in 3 out of the 24 patients in group 2, in whom the medication was continued even after the surgery. There was no sig nificant difference in the incidence of postoperative infections between the two groups. CONCLUSION: From this study, postoperative use of antibiotics seems to be unnecessary with view of the little significance of the factors that could affect the wound infection.
