Granular Cell Tumors of the Abdominal Wall.
10.3349/ymj.2007.48.4.727
- Author:
Jung Suk AN
1
;
Sun Hee HAN
;
Sung Bae HWANG
;
Ju Han LEE
;
Byung Wook MIN
;
Jun Won UM
;
Eung Seok LEE
;
Heum Rye PARK
;
Young Sik KIM
Author Information
1. Department of Pathology, Ansan Hospital, Medical College, Korea University, Ansan, Korea. repath@korea.ac.kr
- Publication Type:Case Report
- Keywords:
Granular cell tumor;
abdominal wall;
ultrastructure
- MeSH:
Abdominal Neoplasms/metabolism/*pathology;
Adult;
Female;
Granular Cell Tumor/metabolism/*pathology;
Humans;
Immunohistochemistry;
Rectus Abdominis/metabolism/*pathology;
S100 Proteins/metabolism
- From:Yonsei Medical Journal
2007;48(4):727-730
- CountryRepublic of Korea
- Language:English
-
Abstract:
Granular cell tumors (GCT) are found in virtually any body site, including the tongue, skin, subcutaneous tissue, breast, rectum and vulva. However, they are rarely seen in the abdominal wall. We report here on a rare case of GCT in the rectus muscle of the abdominal wall. A 44-year-old woman presented with a non-tender, hard mass in the right lower abdominal wall. Upon microscopic examination, the tumor was found to comprise of large polygonal cells with an abundant eosinophilic granular cytoplasm and round to oval nuclei. Upon immunohistochemical staining, the large cells showed S-100 and CD68 positive granular aggregates in the cytoplasm. Many lysosomes of variable size were observed in the cytoplasm.