Polyvesicular Vitelline Tumor of the Ovary: A case report .
- Author:
Woo Sung MOON
;
Dong Geun LEE
- Publication Type:Case Report
- Keywords:
Polyvesicular vitelline tumor;
Yolk sac
- MeSH:
Adult;
Cytoplasm;
Endodermal Sinus Tumor;
Epithelial Cells;
Female;
Fetal Proteins;
Humans;
Hyalin;
Microscopy;
Mitosis;
Ovary*;
Vitellins*;
Yolk Sac
- From:Korean Journal of Pathology
1999;33(11):1102-1106
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Polyvesicular vitelline tumor of the ovary is an extremely rare variant of yolk sac tumor. We present a case of pure polyvesicular vitelline tumor in a 43-year-old woman. Light microscopy revealed a predominantly polyvesicular pattern embedded in mesoblastic stroma with the cysts showing two type of lining; tall columnar and cuboidal, or mesothelioid cells. The lining atypical cells showed occasional mitoses and intracytoplasmic PAS positive hyaline globules. In some areas, the cystic space contained a large amount of intraluminal hyaline material. Immunohistochemically, alpha- fetoprotein and alpha-1-antitrypsin were detected as a fine granular deposit in the cytoplasm of epithelial cells and hyaline globules. Electron microscopically, marked specialization of the vesicular lining cells suggested a differentiation toward gut structures and mature yolk sac.
