Incidence of eNOS gene mutationin Korean patients with coronary artery spasm.
10.4070/kcj.2001.31.5.512
- Author:
Jung Hee KIM
;
Byung Kwan LIM
;
Bo Young KIM
;
Jeong Woo LEE
;
Jung A KANG
;
Dae Seung LIM
;
Min Soo LEE
;
Yoon Cheol KIM
;
Bo Young SUNG
;
Seong Choon CHOE
;
In Whan SEONG
;
Eun Seok JEON
- Publication Type:Original Article
- MeSH:
Cholesterol;
Chungcheongnam-do;
Coronary Vessels*;
DNA;
Female;
Humans;
Incidence*;
Korea;
Male;
Myocardial Ischemia;
Nitric Oxide;
Nitric Oxide Synthase Type III;
Polymerase Chain Reaction;
Prevalence;
Smoke;
Smoking;
Spasm*;
Triglycerides
- From:Korean Circulation Journal
2001;31(5):512-512
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Coronary artery spasm is an important mechanism in producing myocardial ischemia. But the exact mechanism of the spasm is not well known. We investigated the mutation of endothelial nitric oxide synthase (eNOS) that produce nitric oxide and relationship between eNOS mutation and coronary artery spasm. MATERIALS AND METHODS: Blood were drawn from the patients with angiographically proven coronary artery spasm and normal controls. DNA were extracted and polymerase chain reaction and restriction analysis with Nae I were performed to find T-786--
