The Effect of Capsaicin Spray in Nasal Hyperreactivity.
- Author:
Tae Young JANG
1
;
Seung Yoeung SONG
;
Tae Man KIM
Author Information
1. Department of Otorhinolaryngology, College of Medicine, InHa University, Incheon, Korea. JangTY@inha.ac.kr
- Publication Type:Original Article
- Keywords:
Capsaicin;
Hypersensitive rhinitis
- MeSH:
Capsaicin*;
Capsicum;
Humans;
Nasal Mucosa;
Nasal Obstruction;
Pruritus;
Rhinitis;
Sneezing
- From:Journal of Rhinology
2001;8(1, 2):58-62
- CountryRepublic of Korea
- Language:English
-
Abstract:
Capsaicin, a nonenamide derived from Capsicum plants, has proven to be useful in patients with vasomotor rhintitis. In this study, we estimated the effects of 10-5 M capsaicin spray in patients with hypersensitive rhinitis. The drug was given 3 times per day for 3 days to each patient by means of a spray delivered to the nasal mucosa. Patient's symptom score was recorded by the same physician. We repeated this method after 1 week, 2 week, 4week, 8week, 12week, 16week and recorded their symptom score. As a result, the mean symptom score involving nasal obstruction, sneezing, rhinorrhea and itching was remarkably reduced by capsaicin spray. The present findings suggest that capsacine spray is a good therpheutic method for hypersensitive rhinitis patients.
