Some biological effects of flavonoid product extracted from fruit calyces of Hibiscus sabdariffa Linn. grew in Vietnam
- Author:
Huu Duc Phung
- Publication Type:Journal Article
- Keywords:
flavonoid
- MeSH:
Flavonoids;
Plants, Medicinal
- From:Pharmaceutical Journal
2000;291(7):10-13
- CountryViet Nam
- Language:Vietnamese
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Abstract:
The bioactivity of flavonoid from H. sabdariffa growing in Vietnam have been investigated (signed by FHS). FHS have different effect on the inhibition of the growth and development of bacteria and fungus. Their good effects on the peroxydase activity in human blood and their liver protection from destroy by CCl4 has been expressed the antioxidant potency. On the basic of this antioxidant activity of flavonoid, the investigation of flavonoids effects on cancer cell sarcoma-180 have been realized and show that FHS could inhibit the mitosis of cancer cells. The in vivo tests have been realized on experimental animals. An optimal dose to reach the efficiency was determined (in vitro and in vivo). This result opened a perspective to apply the flavonoids of H. sabdariffa for anticancer therapy, chiefly for pre-cancer period.
