Hypereosinophilic Syndrome : CT Findings in Patients with Hepatic Lobar or Segmental Involvement.
- Author:
Jae Hoon LIM
1
;
Won Jae LEE
;
Dong Ho LEE
;
Kyung Jin NAM
Author Information
- Publication Type:Original Article
- Keywords: Liver, CT; Liver, abscess; Liver, disease
- MeSH: Adult; Female; Human; Hypereosinophilic Syndrome/pathology/*radiography; Liver/pathology; Liver Diseases/pathology/*radiography; Male; *Tomography, X-Ray Computed
- From:Korean Journal of Radiology 2000;1(2):98-103
- CountryRepublic of Korea
- Language:English
- Abstract: OBJECTIVE: The purpose of this study was to describe the CT findings of hepatic hypereosinophilic syndrome in which hepatic lobes or segments were involved. MATERIALS AND METHODS: Seven patients with hypereosinophilic syndrome with hepatic lobar or segmental involvement were included in our study. In all seven, diagnosis was based on liver biopsy and the results of corticosteroid treatment. CT findings were retrospectively reviewed by three radiologists, who reached a consensus. Biopsy specimens were examined, with special reference to portal and periportal inflammation. RESULTS: CT demonstrated well-defined, homogeneous or heterogeneous low attenuation with a straight margin limited to a hepatic lobe (n = 2), segments (n = 3), or subsegments (n = 2), particularly during the portal phase. Where there was subsegmental involvement, lesions were multiple, ovoid or wedge-shaped, and showed low attenuation. In two patients with lobar or segmental involvement, segmental portal vein narrowing was observed. Histopathologic examination dis-closed eosinophilic infiltration in the periportal area, sinusoids and central veins, as well as portal phlebitis. CONCLUSION: Hypereosinophilic syndrome may involve the presence of hepatic lobar, segmental, or subsegmental low-attenuated lesions, as seen on CT images. Their presence may be related to damage of the liver parenchyma and to portal phlebitis.
