Disseminated BCG Infection in a patient with Severe Combined Immunodeficiency.

Author: Tae Il HAN ¹ ; In One KIM ; Woo Sun KIM ; Kyung Mo YEON
Author Information

1. Department of Radiology, Eulji University School of Medicine, Seoul, Korea.
Publication Type:Case Reports ; Research Support, Non-U.S. Gov't
Keywords: Bones, infection; Infants, newborn, skeletal system; Tuberculosis, gastrointestinal; Tuberculosis, musculoskeletal
MeSH: *BCG Vaccine; Case Report; Female; Human; Infant; Mycobacterium bovis; Severe Combined Immunodeficiency/*immunology; Tomography, X-Ray Computed; Tuberculosis/*immunology/radiography/ultrasonography
From:Korean Journal of Radiology 2000;1(2):114-117
CountryRepublic of Korea
Language:English
Abstract: Disseminated mycobacterial infection after bacillus Calmette-Guerin (BCG)vaccination is a very rare disorder, occurring mostly in patients with immunologic deficiency. We report a case of disseminated BCG infection in a 16-month-old girl with severe combined immunodeficiency. Plain radiographs showed multiple osteolytic lesions in the femora, tibiae, humerus, and phalanges. Abdominal sonography and CT scanning revealed multiple nodules in the spleen, and porto-caval lymphadenopathy.