Impact of the interval between coronary angiography and off-pump coronary bypass surgery on postoperative renal function.
10.4097/kjae.2010.58.2.142
- Author:
Na Young KIM
1
;
So Yeon KIM
;
Na Hyung LEE
;
Young Lan KWAK
Author Information
1. Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine, Seoul, Korea.
- Publication Type:Original Article
- Keywords:
Coronary angiography;
Kidney;
Off-pump coronary artery bypass;
Postoperative periods
- MeSH:
Acute Kidney Injury;
Angiotensin Receptor Antagonists;
Angiotensin-Converting Enzyme Inhibitors;
Coronary Angiography;
Coronary Artery Bypass;
Coronary Artery Bypass, Off-Pump;
Creatinine;
Cystatin C;
Diabetes Mellitus;
Emergencies;
Glomerular Filtration Rate;
Heart Failure;
Hematocrit;
Humans;
Hypertension;
Incidence;
Kidney;
Postoperative Period;
Renal Insufficiency, Chronic;
Renal Replacement Therapy;
Stroke Volume
- From:Korean Journal of Anesthesiology
2010;58(2):142-147
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND: Postoperative acute kidney injury (AKI) is a significant complication after coronary artery bypass surgery. Prior coronary angiography increases the likelihood of AKI due to the use of a radiocontrast dye. This study examined the effect of coronary angiography on the postoperative renal function after off-pump coronary artery bypass surgery (OPCAB). METHODS: The records of 110 patients who required OPCAB were reviewed. These patients also had at least two of the following conditions: chronic kidney disease, hypertension, diabetes mellitus, emergency surgery, congestive heart failure, age >75 years, hematocrit <30%, a left ventricular ejection fraction <40%, or the use of angiotensin-converting enzyme inhibitors or angiotensin receptor blockers. The patients were divided into two groups; coronary angiography performed within two days of OPCAB (Control group, n = 55), and coronary angiography performed more than two days before OPCAB (Angio group, n = 55). The serum creatinine (SCr) and serum cystatin C levels were measured on the day before surgery, as well as on postoperative days 1, 2, 3 and 7. The estimated glomerular filtration rate (eGFR) was also obtained on those days. AKI was defined as an increase in Cr > or =50% or > or =0.3 mg/dl within 48 hours. RESULTS: The postoperative changes in the SCr, cystatin C and eGFR were similar in the two groups. The incidence of AKI and renal replacement therapy were similar in the two groups. CONCLUSIONS: Coronary angiography performed within two days of OPCAB does not affect the postoperative renal function.