Osteoclast-like Giant Cell Tumor of Parotid Gland with a Carcinomatous Component: A Case Report.
10.4132/KoreanJPathol.2012.46.3.297
- Author:
Jung Wook YANG
1
;
Hyeon Cheol KIM
;
Jeong Hee LEE
;
Jong Sil LEE
;
Dong Chul KIM
;
Dae Hyun SONG
;
Jin Pyeong KIM
;
Gyung Hyuck KO
Author Information
1. Department of Pathology, Gyeongsang National University School of Medicine, Jinju, Korea. gyunghko@gnu.ac.kr
- Publication Type:Case Report
- Keywords:
Giant cell tumors;
Salivary glands
- MeSH:
Male;
Humans;
Neoplasm Metastasis
- From:Korean Journal of Pathology
2012;46(3):297-301
- CountryRepublic of Korea
- Language:English
-
Abstract:
The giant cell tumor of the salivary gland is very rare, and 20 cases have been reported in the English-language literature. We report an additional case. A 57-year old man had noticed a mass in the right parotid area for several weeks. The diagnosis using aspiration cytology was a giant cell tumor possibly with a carcinomatous component. Superficial parotidectomy was carried out. The resected parotid gland contained a 1.8 cm-sized well-circumscribed brownish tumor. Histologically the tumor consisted of evenly distributed osteoclast-like giant cells, mononuclear cells and two small foci of a carcinomatous component. The osteoclast-like giant cells and mononuclear cells were positive for vimentin and CD68, and the carcinomatous component was positive for cytokeratin and epithelial membrane antigen. There was no metastatic lesion in the cervical lymph nodes. We believe this is the first case in Korea of an osteoclast-like giant cell tumor of the parotid gland.
