The significance of the TDx-FLM assay in the fetal lung maturity.
- Author:
Moon Whan IM
1
;
Wonsick CHOE
;
Sung Ook HWANG
;
Tae Yul HWANG
;
Jeong Rye LEE
;
Jee Hyun PARK
;
In Hwa NOH
;
Seung Kwon KOH
;
Byoung Ick LEE
;
Woo Young LEE
;
Yun Chul HONG
;
Moon Soo KANG
;
Soo Hwan PAI
Author Information
1. Department of Obstetrics and Gynecology, College of Medicine, Inha University.
- Publication Type:Original Article
- Keywords:
TDx-FLM assay;
Amniostat-FLM assay
- MeSH:
Agglutination Tests;
Amniotic Fluid;
Female;
Fluorescence;
Gestational Age;
Humans;
Lung*
- From:Korean Journal of Obstetrics and Gynecology
2001;44(11):1968-1972
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
OBJECTIVE: The TDX analyzer, an automated fluorescence polarimeter, has been utilized to assess surfactant content in amniotic fluid. Amniostat-FLM is an immunologic semiquantitative agglutination test for determining the presence of phosphatidylglycerol in human amniotic fluid at concentration indicative of fetal lung maturity. We evaluated the usefulness of the recently introduced TDx-FLM assay in determining fetal lung maturity. METHODS: Seventy-three samples of amniotic fluid were analyzed. Among them, 18 samples were compared with Amniostat-FLM assay. RESULTS: Surfactant/albumin ratio using TDx-FLM assay increased with longer gestational age. And the concordance rate between Amniostat-FLM assay and TDx-FLM assay was 66.9%. CONCLUSION: The TDx-FLM assay appears to be a useful test in the field of fetal lung maturity testing.
