A Case of Nicolau Syndrome Treated by Surgical Excision.
- Author:
Bon Seok KU
1
;
Yeong Kyu LEE
;
Oh Eon KWON
;
Chae Wook LEE
;
Ki Ho KIM
Author Information
1. Department of Dermatology, College of Medicine, Dong-A University, Busan, Korea. khkim@dau.ac.kr
- Publication Type:Case Report
- Keywords:
Diclofenac sodium;
Embolia cutis medicamentosa;
Nicolau syndrome
- MeSH:
Adult;
Buttocks;
Diclofenac;
Humans;
Injections, Intramuscular;
Necrosis;
Skin;
Thrombosis
- From:Korean Journal of Dermatology
2006;44(12):1464-1466
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Nicolau syndrome or embolia cutis medicamentosa is an acute necrotic condition of skin that follows intramuscular injection of drugs. A 36-year-old man developed a painful, purpuric and erythematous patch on his left buttock following an intramuscular injection of diclofenac sodium. Histologically, the patch lesion displayed epidermal necrosis, dermal degeneration, and vascular thrombosis. We report a rare case of Nicolau syndrome following intramuscular injection of diclofenac sodium. In our case, the patient was successfully treated by surgical excision with primary closure.
