Antifungal Activity of the Essential oil from Eucalyptus and Eucapytol against Candida albicans.
- Author:
Inwha SEONG
1
Author Information
1. Department of Microbiology, College of Medicine, Korea University, Korea. inwha@korea.ac.kr
- Publication Type:Original Article
- Keywords:
Eucalyptus oil;
Eucapytol;
Antifungal activity;
Candida albicans
- MeSH:
Candida;
Candida albicans;
Candidiasis;
Citrus sinensis;
Eucalyptus;
Gastrointestinal Tract;
Mucous Membrane;
Plants, Medicinal;
Skin;
Wood
- From:Korean Journal of Medical Mycology
2009;14(3):127-132
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
BACKGROUND: Candida albicans is a member of the normal flora of the skin, mucous membranes and gastrointestinal tract. Vaginal candidiasis remains a significant problem in women OBJECTIVE: The purpose of this study was to develop the antifungal agent from the medicinal herbs traditionally used in Korea. Method: In this study, the essential oil of eucalyptus, cedar wood, clary sage, orange sweet and eucapytol were examined for antifungal activities against C. albicans. RESULTS: 1. Eucalyptus essential oil and eucapytol showed antifungal activity against C. albicans. 2. Minimal inhibitory concentration (MIC) of Eucapytol against eight strains and standard strains was 12.5 microliter/ml and 6.25 microliter/ml against two strains. 3. MIC of eucapytol was 25 microliter/ml against eight strains and 50 microliter/ml against two. CONCLUSION: Eucalyptus essential oil and eucalytol could be a candidate for a new antifungal agent for candidiasis and other fungal diseases.
