Chronic Cavitary Pulmonary Histoplasmosis in a Non-HIV and Immunocompromised Patient without Overseas Travel History.
10.3349/ymj.2015.56.3.871
- Author:
Eun Ju JUNG
1
;
Dae Won PARK
;
Jung Woo CHOI
;
Won Suk CHOI
Author Information
1. Division of Infectious Diseases, Department of Internal Medicine, Korea University College of Medicine, Seoul, Korea. cmcws@medimail.co.kr
- Publication Type:Case Reports
- Keywords:
Histoplasma capsulatum;
immunocompromised host;
Korea
- MeSH:
Aged;
Antifungal Agents/therapeutic use;
Biopsy;
Female;
Histoplasma/*isolation & purification;
Histoplasmosis/*diagnosis/drug therapy/microbiology;
Humans;
*Immunocompromised Host;
Itraconazole/therapeutic use;
Lung Diseases, Fungal/*diagnosis/drug therapy;
Republic of Korea;
Tomography, X-Ray Computed;
Treatment Outcome
- From:Yonsei Medical Journal
2015;56(3):871-874
- CountryRepublic of Korea
- Language:English
-
Abstract:
Korea is not known as an endemic area for Histoplasma. However, we experienced a case of histoplasmosis in a person who had never been abroad. A 65-year-old female was admitted to the hospital for evaluation of multiple lung nodules. A computed tomography (CT) scan of the chest showed multiple ill-defined consolidations and cavitations in all lobes of both lungs. The patient underwent a CT-guided lung biopsy, and a histopathology study showed findings compatible with histoplasmosis. Based on biopsy results and clinical findings, the patient was diagnosed with chronic cavitary pulmonary histoplasmosis. The patient recovered completely following itraconazole treatment. This is the first case report of pulmonary histoplasmosis unconnected with either HIV infection or endemicity in Korea.
