Human prenatal sex determination using multiplex polymerase chain reaction (PCR)
- Author:
Lan Thi Ngoc Hoang
- Publication Type:Journal Article
- Keywords:
fetus
- MeSH:
Fetus;
Neural Tube Defects;
Aneuploidy
- From:Journal of Medical Research
1999;9(1):3-7
- CountryViet Nam
- Language:Vietnamese
-
Abstract:
A sex determination method has been developed using the polymerase chain reaction (PCR) which involved the amplification of sex determining region Y (SRY) gene and the amplification of the HLA-DQ gene as an internal control, in the one PCR reaction using two sex of the primers. The PCR products were sort ADN of 139 bp for SRY and 239/242 bp for HLA-DQ region spectively. The amplification of this method in prenatal diagnosis to prevent genetic diseases, in forensic science.
