A Case of Membranous Nephropathy in a Patient with Pulmonary Silicosis.
- Author:
Hye Jung HA
1
;
Hyun Jung KIM
;
Su Hi KIM
;
Geoung Won LEE
;
Tae Hyo KIM
;
Young Mi CHOI
;
Jung Ill YANG
;
Un Sil JEON
;
Se Ho CHANG
Author Information
1. Department of Internal Medicine, College of Medicine, Gyeongsang National University, Chinju, Korea.
- Publication Type:Case Report
- Keywords:
Silicosis;
Membranous nephropathy;
Nephrotic syndrome
- MeSH:
Antibodies, Antinuclear;
Atrophy;
Biopsy;
Cyclophosphamide;
Dyspnea;
Edema;
Glomerulonephritis;
Glomerulonephritis, Membranous*;
Hematuria;
Humans;
Korea;
Middle Aged;
Nephrotic Syndrome;
Proteinuria;
Silicosis*;
Thorax
- From:Korean Journal of Nephrology
2001;20(3):535-539
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
A 63-year old man, who was a stone mason, was hospitalized due to dyspnea and generalized edema. Chest X-ray showed the presence of multiple scattered small nodular opacities in both lobes and egg-shell calcification in both hilum. Laboratory finding showed proteinuria and hematuria and antinuclear antibody was positive. Renal biopsy revealed membranous nephropathy and tubular atrophy. He was treated with cyclophosphamide, but proteinuria has been sustained. In literature reviewed, silicosis was associated with various forms of glomerulonephritis, but in Korea, such case has not been reported except the one case of microscopic polyangitis with membranous glomerulonephropathy associated with pulmonary silicosis. We experienced membranous nephropathy in a patient with pulmonary silicosis, thus we report it.
