Type 2 Diabetes and Mitochondria.
10.3803/jkes.2006.21.4.266
- Author:
Hyo Jung CHOO
1
;
Young Gyu KO
Author Information
1. School of Life Sciences and Biotechnology, Korea University, Korea.
- Publication Type:Review
- MeSH:
Adipose Tissue;
Humans;
Insulin;
Liver;
Mitochondria*
- From:Journal of Korean Society of Endocrinology
2006;21(4):266-271
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Liver, muscle, and adipose tissue are resistant to insulin action in type 2 diabetes. In spite of intensive studies, few diabetic genes have been identified. Recently, mitochondrial impairment has been observed in the muscle and adipose tissues of type 2 diabetes patients, implying that mitochondrial dysfunction could be a pivotal factor in type 2 diabetes. Here, we discuss mitochondrial malfunction leading to type 2 diabetes.
