A Case of Sheehan's Syndrome Presenting Central Diabetes Insipidus.
10.3803/jkes.2006.21.4.333
- Author:
Dong Jin KIM
1
;
Nan Hee KIM
;
Ju Ri PARK
;
Sae Jeong YANG
;
Hye Suk KIM
;
Hye Jin YOO
;
Soo Yeon PARK
;
Ohk Hyun RYU
;
Kye Won LEE
;
Hee Young KIM
;
Ji A SEO
;
Sin Gon KIM
;
Kyung Mook CHOI
;
Sei Hyun BAIK
;
Dong Seop CHOI
Author Information
1. Department of Internal Medicine, Korea University College of Medicine, Korea.
- Publication Type:Case Report
- Keywords:
Central diabetes insipidus;
Hypopituitarism;
Postpartum hemorrhage;
Sheehan's syndrome
- MeSH:
Blood Transfusion;
Diabetes Insipidus;
Diabetes Insipidus, Neurogenic*;
Growth Hormone;
Hemorrhage;
Humans;
Hypopituitarism*;
Necrosis;
Pituitary Gland, Anterior;
Pituitary Gland, Posterior;
Pituitary Hormones, Anterior;
Postpartum Hemorrhage;
Prolactin;
Water Deprivation
- From:Journal of Korean Society of Endocrinology
2006;21(4):333-337
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Sheehan's syndrome occurs as a result of ischemic pituitary necrosis due to severe postpartum hemorrhage. The manifestations of this clinical syndrome are most often caused by a deficiency in the hormones produced by the anterior pituitary gland, whereas the neurohypophysis is usually preserved but can be involved in severe cases that manifest as diabetes insipidus. This is a report of Sheehan's syndrome that manifested with diabetes insipidus as presenting symptom 2 month's after delivery. The patient suffered massive bleeding, so received a blood transfusion. A combined pituitary stimulation and water deprivation test revealed deficiencies of not only anterior pituitary hormones, such as growth hormone and prolactin, but also of anti-diuretic hormone. We report this case, with a review of the literature.
