Fractionated Stereotactic Gamma Knife Radiosurgery for Medial Temporal Lobe Epilepsy: A Case Report.
- Author:
Hye Ran PARK
1
;
Hyun Tai CHUNG
;
Sang Kun LEE
;
Dong Gyu KIM
;
Sun Ha PAEK
Author Information
- Publication Type:Case Report
- Keywords: Radiosurgery; Stereotaxic Techniques; Epilepsy
- MeSH: Adolescent; Epilepsy; Epilepsy, Temporal Lobe*; Humans; Intellectual Disability; Male; Radiosurgery*; Seizures; Stereotaxic Techniques; Temporal Lobe*
- From:Experimental Neurobiology 2016;25(2):93-101
- CountryRepublic of Korea
- Language:English
- Abstract: An 18-year-old left-handed male harbored intractable medial temporal lobe epilepsy (MTLE) underwent fractionated gamma knife surgery (GKS) instead of open surgery, considering the mental retardation and diffuse cerebral dysfunction. GKS treatment parameters were: target volume, 8.8 cm3; total marginal dose, 24 Gy in 3 fractionations at the 50% isodose line. The patient has been free from seizures since 9 months after GKS, with notable improvement in cognitive outcome. Fractionated GKS could be considered as a safe tool for seizure control and neuropsychological improvement in patients with MTLE.
