A Case of Herpes Simplex Virus Esophagitis in a Renal Transplant Child.
- Author:
Ji Ah JUNG
;
Eun Woo SHIN
;
Kyung Dan CHOI
;
Jae Sung KO
;
Jeong Wan SEO
;
Jeong Kee SEO
- Publication Type:Case Report
- MeSH:
Acyclovir;
Child*;
Chromatin;
Esophagitis;
Esophagus;
Exudates and Transudates;
Giant Cells;
Herpes Simplex*;
Humans;
Inflammation;
Kidney Transplantation;
Male;
Nausea;
Simplexvirus*;
Transplantation;
Ulcer;
Vomiting
- From:Korean Journal of Gastrointestinal Endoscopy
2002;24(3):143-146
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
Herpes simplex esophagitis can occur in those with normal immune function, but is more often seen in those who are immunocompromised. In one series, 5 percent of post-kidney transplant recipients had herpes esophagitis. We experienced a case of herpes simplex esophagitis, following renal transplantation in a 9 year old male. He complained of epigastric pain, nausea and blood-tinged vomiting. Endoscopic examination showed volcano ulcer, mucosal friability and multiple confluent ulcers covered by whitish exudates on elevated margin in the middle and lower esophagus. Microscopic findings revealed multinucleated giant cells, margination of chromatin, intense nonspecific inflammation and strong positive for herpes simplex virus immunohistochemical staining. Esophageal lesions and symptoms improved after acyclovir therapy.
